Based in our Edinburgh centre, the MND-SMART trial is a flagship national clinical trial designed with patients in mind. It has broad inclusion criteria, so that most people are eligible, and recruits at many centres, so that it is highly accessible to people with MND who might not live near a large research centre. All drugs are liquid based, there is twice the chance of being on active treatment as on placebo, and crucially, the trial is a platform adaptive design. That means several treatments can be tested at the same time, and can move from Phase 2 to Phase 3, greatly increasing the speed at which new drugs can be tested.
What we gain from this:
MND-SMART is a rapid, patient-friendly way to test new treatments.